Is I am at risk of getting cancer if....................? Mostly children (sometime parents) ask this question. Today again. So, i tried to explain them that Usually NOT. About 10% of cases can be hereditary. Generally, if a person having some special pathology and risk factors then he is suspected for familial cancer. Risk factors for possibility of presence of genetic mutation are- A. If your brother or father has been detected for high risk, advanced or metastatic prostate cancer at age below 60 year, B. Biopsy is having intraductal or cribriform pattern, C. If first degree relative died of Prostate Cancer. Investigation for testing of presence of Genetic mutation- If above, then send family member for counseling with "Genetic counselor". Based on case history and available facts, he may decide need of "Germline" or "Somatic" testing for presence of pathogenic mutation that are responsible for developing cancer. These genetic mutations are Lynch
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