No need to remove part of upper or lower limb OR to go for costly prosthesis when cheaper alternative are available for treatment of bone tumour

Ewing sarcoma or other bone tumour mostly involve removal of limb and permanent disability. Even though, possibility of cure is low. Most of patient developed recurrence in lung or other organs which make incurable situations and people live with poor quality of disabled life. Then, one should not go for amputation when limb preserving treatment are oncologically safe and give same level of survival with good quality of life. Today, we saved a leg of a child from bone tumour by doing Extracorporeal Radiation therapy. Extracorporeal radiation therapy is one of safe, effective and cheap treatment option. It this process oncosurgeon remove diseased portion of bone and radiation oncologist sterilize bone by killing all cancer cell using ablative dose of radiation therapy to excised bone. This sterilized bone is now used as prosthesis / implant. Benefits of this implant / prosthesis is 1) free of cost, 2) part of his / her own body and 3) avoid need of postoperative radiation treatment.

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Is I am at risk of getting Prostate cancer or other cancer if my parent have cancer? Who can be screened for possibility or presence of Hereditary Prostate Cancer?

Is I am at risk of getting cancer if....................? Mostly children (sometime parents) ask this question. Today again. So, i tried to explain them that Usually NOT. About 10% of cases can be hereditary. Generally, if a person having some special pathology and risk factors then he is suspected for familial cancer. Risk factors for possibility of presence of genetic mutation are- A. If your brother or father has been detected for high risk, advanced or metastatic prostate cancer at age below 60 year, B. Biopsy is having intraductal or cribriform pattern, C. If first degree relative died of Prostate Cancer. Investigation for testing of presence of Genetic mutation- If above, then send family member for counseling with "Genetic counselor". Based on case history and available facts, he may decide need of "Germline" or "Somatic" testing for presence of pathogenic mutation that are responsible for developing cancer. These genetic mutations are Lynch

Is every enlargement of Prostate gland due to cancer or something else? Difference in BPH vs Prostate Cancer?

Enlargement of prostate gland can be due to 1. Prostate Cancer and 2. BPH. Prostate Cancer- What is Prostate Cancer? Cancer is abnormal growth and uncontrolled growth of any cell in the body that leads to development of swelling or tumor. When this happen in the cells of prostate then it called prostate cancer. In case of cancer, single of multiple, small tumors start growing inside prostate gland. These cells are continuously dividing and growing. This causes development of many swelling / tumor inside prostate that looks like irregular enlargement of prostate. Is it life threatening? Sometime, these cells escape from prostate and spreads throughout body via blood or lymph and make many tumor in other organs of body like lung, liver, bone or brain. When these cancer are confined inside prostate is called localized stage of prostate cancer, when it spread up to nearby regional lymph nodes then called Node positive Prostate Cancer or when spread to other organs like lung then calle

Importance of Lateral Rectal Lymph node in Low Rectal Cancer

1. A case of Lateral Rectal LNs failure, 2. Concept of Lateral Lymph node involvement Reference 1: Key Factor Sammour T, Chang GJ. Lateral pelvic lymph node dissection and radiation treatment for rectal cancer: Mutually exclusive or mutually beneficial?Ann Gastroenterol Surg. 2018;00:1–3. https://doi.org/10.1002/ags3.12197 . LRLN in case of low or mid RC should be considered as a part of regional disease and to be mutually addressed during nCRT & Sx. Low risk of LPLN disease (cT1/T2/early T3) (and Ra*) with cN0-LPLN on MRI: Treatment by TME. Moderate risk of LPLN disease (cT3/4 with cN0-LPLN on MRI <7mm) (or Rb**): treatment by nCRT + TME +/- LPLND. High risk of LPLN disease (cN1-LPLN on MRI >7mm) (Ra or Rb): treatment by nCRT + TME + LPLND. * Ra- above peritoneal reflection **Rb-below peritoneal reflection. Reference 2: Key Factors- Ogura A et al. Neoadjuvant (Chemo)radiotherapy With Total Mesorectal Excision Only Is Not Sufficient t

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